Healthcare » Drug Delivery, Development and Screening

Found 7 technologies within Drug Delivery, Development and Screening RSS ATOM

New Local Anesthetic Solution Minimizes Injection-Related Pain and Extends Limited Lidocaine Supplies

33832 – Improved Lidocaine Formulation Minimizes Pain at Injection Site While Maintaining Effectiveness Administered in more than 1 million cutaneous surgeries per year, local anesthesia injections are viewed as a very painful part of minor surgery. Additionally, the lidocaine for such formulations is in short supply. In response to these issues, UCF researchers have developed a new... Read More

Block diagram of the experiment used to determine the emission spectra of the samples

Technique for Tagging Therapeutically Relevant Compounds for Tracking and Evaluation Using Infrared Excitation Sources

31590 – Methods, apparatus and systems for doping cerium oxide and other therapeutically valuable nanoparticles with rare earth ions so that infrared light is absorbed and visible light is emitted through the process of up-conversion Nanoparticles are increasingly being used in the biological sciences for various therapeutic and research purposes. Nanoceria, for example, is a potentially powerful... Read More

Full length (LIMK), constitutively active phosphomimic (LIMKCA), LIMdomain only (LIMKLD), and kinase-domain only (LIMKKD) LIMK1 constructs were cloned into the pCMV14 vector used for expression in RWPE1 cells

Inhibiting Proliferation and Metastasis of Cancer Cells

32194 – This discovery provides methods and compounds for decreasing the expression of LIMK1 and AurKA in cancer cells. Metastasis of tumor cells contributes to about 90% of cancer-related deaths. Proteins that regulate cell motility are attractive targets for cancer therapy because they can also play key roles in cell survival, proliferation, and migration. Lim kinase 1 (LIMK1) is a protein that... Read More

Flow chart that shows steps in an example method for forming functionalized particles, according to an example embodiment

Micro- and Nano-Scale Polymeric Particle Fabrication

33036 – By forming a polymer casing that can encapsulate nanoparticles to deliver them to specific locations in the human body based on the polymer spheres’ shape, researchers have developed a technology to advance biomedical treatment and diagnosis. This ability to produce polymeric particles with a size, shape, and composition that determines finely-tuned physiochemical properties is made more... Read More

Display of a method of preparing a carbon fiber from a fiber component

An Environmentally Friendly Approach to Cost-Effectively Produce Oxidized Graphite and Prepare Carbon Fiber

32747 – Researchers at the University of Central Florida (UCF) have developed a scalable, environmentally friendly method to produce oxidized graphite. UCF’s oxidized graphite is water dispersible, which aids in the preparation of thin films, carbon fibers, and carbon nanotubes; has resistivities ranging from 50-8,000 Ω/cm2; and, most importantly, allows for easy conversion to graphene. Oxidized... Read More

Polyamines Used for a Variety of Functions

30810 – Polyamines are required in many cellular processes of both eukaryotic and prokaryotic cells. Polyamines contribute to regulation of cell proliferation, cell differentiation, and homeostasis, and have been shown to play specific roles in replication, transcription, and translation. Studies have shown that cancer cells up-regulate polyamine transporters thereby taking in drastically more... Read More

Representation of a mobile phone and a fluorimeter of the portable spectrometer system generating and collecting an emission spectrum of a test strip with an unknown substance in accordance with the present invention.

Rapid Drug Identification Kit

32772 – For drug analysts, it is difficult to identify certain types of drugs. Additionally, the frequency of new drugs introduced is at an alarming rate and this enhances the problem faced by the drug analysts. To help the drug analysts in the field, there are many reagent kits available to identify certain drugs based on the color they generate when reacted with the reagents. However, the... Read More