Simultaneous Spatial Imaging and Spectral Sensing for the Diagnosis of Cervical and Skin Cancers

Technology #30450

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Perspective view of a first preferred embodiment of the novel probe and receiver device for simultaneous acquisition of spatial and spectral OCT (SI-OCT)
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Researchers
Peter Delfyett, Ph.D.
Jannick Rolland, Ph.D.
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John Miner
Assistant Director 407.882.1136
Patent Protection

Optical disk readout method using optical coherence tomography and spectral interferometry

US Patent 6,072,765

Three dimensional optical imaging colposcopy

US Patent 5,921,926

A probe that simultaneously performs optical coherence tomography (OCT) and spectral analysis using back reflected light

The present invention provides a tunable source of low-coherence light to simultaneously conduct spatial imaging and spectral sensing for tissue diagnosis. It offers a real time three dimensional colposcopy diagnosis and the detailed guidance to physically biopsy suspicious lesions. This all-in-one probe eliminates the old techniques of having to perform pap smears followed by a colposcopy, assuring efficiency and a better chance of recovery for patients, including pregnant patients.

Technical Details

UCF researchers have developed an optical coherence tomography (OCT) and spectral interferometry imaging probe for the automatic screening and diagnosis of cervical and skin cancer in vivo. This revolutionary probe eliminates the old and inefficient techniques of having to perform pap smears followed by a biopsy, known as colposcopy. Following an abnormal pap smear, a patient is recommended for a colposcopy, where a colposcope is used to attempt to identify suspect lesions. Subsequent to colposcopy, biopsy of suspected lesions is performed for histology follow up. However, there are several problems with utilizing this method. Patient compliance is a major issue when having a biopsy performed. Fear of having this procedure carried out is a common reason why patients procrastinate and delay the follow up procedures. This in turn hurts their chance of recovery, since cancer is best treated in its earliest stages. Additional problems exist with pregnant patients, because biopsy is not recommended during pregnancy due to increased risk of bleeding. Prior art inventions have failed to adequately cover these problems with a single procedure, as none of them conduct imaging and spectroscopy simultaneously.

Benefits

  • Eliminates the old and inefficient techniques of having to perform pap smears followed by a colposcopy
  • Resultant data transfer rate is increased by simultaneously employing both spectral interferometry and low coherence tomography
  • Performs three dimensional imaging of cavity interior walls, such as, but not limited to a uterus/cervix body area

Applications

  • Automatic screening and diagnosis of cervical and skin cancer in vivo


Additional Technology Numbers: 30434