Technologies Available for Licensing

1-50 of 418 technologies RSS ATOM

Exosome-Based RNAi Delivery for Anti-Cancer and Anti-Viral Therapy

11510 – Researchers at the University of Central Florida have developed an exosome-based approach for treating cancer and viral infections. The exosomes deliver gene-silencing molecules or protein inhibitors such as RNA interference (RNAi) or antibodies, respectively. Because exosomes are endogenous vesicles, this approach may limit immunogenicity and toxicity. For anti-cancer... Read More

Device Cuts and Crimps Tissue for Single-Step Meatotomy

2021-101 – The University of Central Florida invention is a multi-functional surgical device for performing meatotomy procedures without needing additional devices. The device includes a centrally-located blade, flanked on both sides by ridged grooves, allowing it to simultaneously crimp and cut tissue. With the device, the meatotomy procedure can occur in a single step which can improve... Read More

Cobalt- and Nickel-Free Cathode for Lithium-Ion Batteries Can Outperform Existing Cathode Materials

2022-013 – The University of Central Florida invention is a cobalt- and nickel-free lithium-ion cathode with good thermal stability and can achieve a high cell voltage and specific capacity comparable to or exceeding currently used Li(NiCoMn)O2 cathodes. This new cathode chemistry eliminates metal supply issue concerns. It also lowers the cost of the batteries, particularly for electric... Read More

Antimalarial Compounds Combat Drug-Resistant Parasites

11434 – Researchers at the University of Central Florida have developed potent compounds for fighting chloroquine-resistant malaria-causing parasites. The low nanomolar compounds were effective against chloroquine-resistant Dd2 strains of Plasmodium falciparum parasites in vitro and completely cured malaria infection in vivo. The Plasmodium falciparum parasite has developed resistance to... Read More

Organic Non-Wettable Superhydrophobic Fullerite Films

2022-009 – The University of Central Florida invention is a method and composition to produce superhydrophobic, nanostructured fullerite films from colloidal gels. Fullerenes, the only soluble form of pure carbon, possess unique electrical, chemical, and mechanical properties. By creating a non-wettable film, these materials stay dry for up to three hours when submerged in water, enabling... Read More

Heterostructured Thin-Film Catalysts for Solar Energy Harvesting

11249 – Researchers at the University of Central Florida have invented a heterostructured catalyst that increases the energy harvesting capabilities of solar cells. Besides enhancing solar cells and solar fuel cells, it can also function as a photocatalyst for water splitting—the chemical reaction that breaks down water into oxygen (O) and hydrogen (H2). It thus enables a cheaper, more... Read More

Zinkicide®: Particulate-Based Therapeutic Agent Fights Citrus Plant Diseases

10809 – Researchers at the University of Central Florida have developed Zinkicide®, a potent bactericide/fungicide that can effectively treat and prevent diseases in citrus plants and trees such as Huanglongbing (HLB), also called citrus greening. HLB is an invasive citrus disease that is devastating major citrus-producing regions. The disease causes significant crop loss by increasing... Read More

Generate Total Internal Reflection (TIRF) Illumination for High-Resolution Quantitative Fluorescence Microscopy

11627 – The University of Central Florida invention is an imaging method and system that reshapes Total Internal Reflection Fluorescence (TIRF) excitation light into a ring-shaped beam, which is conjugated to the back focal plane of an objective. The output end of the device comprises multiple multi-mode fibers arranged around a spacer to form a single ring. The device enables TIRF... Read More

Polyamine Transport Inhibitors to Activate an Anti-Tumor Immune Response

11057 – Researchers at the University of Central Florida and the Lankenau Institute for Medical Research have synthesized new anti-cancer small molecules that block polyamine uptake and activate the anti-tumor immune response. Many tumors require high levels of polyamines to support their growth and survival. Additionally, high levels of polyamines can suppress the immune system, allowing... Read More

Ultra-Spectrally Selective Terahertz Pyroelectric Detector

11552 – Researchers at the University of Central Florida have invented a device that can intercept electromagnetic radiation in the terahertz (THz) frequency range more effectively without the costly components that other detection methods require. A key aspect of THz radiation is its ability to penetrate a wide range of materials without damaging target objects. Example materials include... Read More

Photochemical Transformation Using Engineered Metal-Free Hexagonal Boron Nitride (h-BN)

2022-001 – The University of Central Florida invention is a process for defect-engineered, 2D-material heterogeneous catalysts. The defect-laden photocatalyst can be used for propene dehydrogenation under visible illumination, and defect engineering in 2D materials provides new opportunities for heterogeneous catalysis. Hydrogenation of propene and the reduction of carbon dioxide (CO2) can... Read More

Weakly-Supervised Grounded Visual Question Answering Using Capsules

2021-076 – The University of Central Florida invention is a capsule network approach to enhance Visual Question Answering (VQA) processes. The invention is a method that applies reasoning within a visual scene to determine a more accurate object, action or relational recognition. Most approaches rely on input feature maps from object detection models that are pretrained with the relevant... Read More

Automated Urban Planning Framework

34582 – The University of Central Florida invention describes an adversarial learning framework that can automatically generate information about land‐use configuration for an unplanned area. Urban planning refers to the efforts of designing land‐use configurations. Effective urban planning can help to mitigate the operational and social vulnerability of an urban system, such as high tax,... Read More

Self-Centering Crucibles for Precision Thermogravimetric Analysis

2021-064 – The University of Central Florida invention describes various designs of self-centering thermogravimetric analysis (TGA) crucibles to allow samples to stay put at a constant location during the measurement process. Thermogravimetric analysis (TGA) measurements are carried out in dedicated systems where the mass of a sample is measured against that of a thermally stable standard.... Read More

Camera-Based System Tracks Fingertip Movement for Touch-Free Computer Manipulation

31207 – Researchers at the University of Central Florida have developed a technology for camera-based fingertip tracking that is less expensive and less complicated than existing methods. The technology enables users to input information into a computer without using conventional mechanisms such as a keyboard, pointing device, mouse, trackpad or touch-sensing displays. Unlike other... Read More

Topical Treatment to Promote Hair Growth

7604 – Researchers at the University of Central Florida are developing a topical treatment to promote hair growth. The active compound is a heterocyclic pyrimidine known as NBI-18. The researchers previously found that NBI-18 stimulated the proliferation of neural stem cells. They hypothesized that NBI-18 could restore hair growth by increasing cell proliferation of endogenous stem cells... Read More

Fast Modal Analysis and Transverse Mode Instability (TMI) Mitigation in High Fiber Amplifiers

11647 – The University of Central Florida invention describes performance improvement methods for high-power laser systems. The techniques include:

User-Accessible Tissue Sample Image Database System

7043 – A University of Central Florida researcher has developed a tissue image database system that enables users to search for and match images based on the presence of a target molecule, internal anatomical structure, or both. The patented system provides powerful tools that can help to expand and support medical and scientific research and informational exchange. For example, a user... Read More

Innovation Enhances Catalyst Activity in High-Energy Ethanol Fuel Cells, Enabling Long-Term Stability, Reduced Degradation

2022-003 – The University of Central Florida invention is a design strategy for discovering new materials and catalysts for energy conversion. The method seeks to regulate the local bonding and local coordination environment (LCE) of the classic metal-nitrogen-carbon (M-N-C) catalysts by infusing fluorine (F)-coordination. As a result, the rationally designed catalyst shows a maximum power... Read More

Spectrally Selective Mid-Infrared (IR) Graphene-VO2 Photodetector Operates Close to Room Temperature

2022-002 – The University of Central Florida invention is an ultrasensitive mid‐infrared (mid‐IR) photodetector consisting of a hybrid heterostructure made of nanopatterned graphene (NPG) and vanadium dioxide (VO2). Compared to current VO2 microbolometers, the graphene‐VO2 photodetector is spectrally selective and has higher sensitivity. The substantial increase in sensitivity is because the... Read More

Generate High-Fidelity Replicas of Target Objects, Including Physical Behavior

11468 – The University of Central Florida invention describes additive manufacturing methods (such as vector fields to guide the propagation of geometry and properties) to design and construct 3D devices, modules, and assemblies. The devices replicate the motion, manipulation, and control of the target objects. The improvements also detail new methods to design, analyze, optimize, and... Read More

Intelligent Digital Interruption Management

2021-108 – The University of Central Florida invention comprises systems and methods for detecting and coordinating interruptions of the playback or generation of time-sequential digital media. Examples of such media include previously recorded digital video/audio stored on the device, previously recorded digital movies/audio streamed from remote servers (over the Internet), and interactive... Read More

Tactile Telepresence for Isolated Patients (TTIP)

11610 – The University of Central Florida invention comprises tactile-visual systems and methods for social interactions between isolated patients (for example, those with COVID-19) and remote visitors such as loved ones, family members, friends, or volunteers. A primary goal is to provide the isolated patient and the remote visitors with a visual interaction augmented by touch—a... Read More

Night-Vision Goggles in the Form of Eyeglasses

2021-073 – The invention developed by the University of Central Florida and Massachusetts Institute of Technology is a night-vision enabling flat lens made of a metamaterial consisting of the following: The flat lens enables all-optical night-vision in the form of eyeglasses without the need for any bulky optical system, electronic transduction and internal screen.

Preserve Nucleic Acids in Water Samples Without Refrigeration

2021-100 – The University of Central Florida invention is a method for preserving nucleic acids in biological materials. It includes a dry nucleic acid preservative reagent that can be used on-site without refrigeration or freezing. The reagent is shelf-stable and does not interfere with the subsequent nucleic acid extraction. Additionally, due to the dry formulation, it can be used with... Read More

Multilayered Carbon Fiber Composite with Superior Strength for High Energy Storage

2021-095 – The University of Central Florida invention is a carbon fiber energy storage system for electric vehicles. The storage devices have an alternating location pattern arrangement of cathode/anode mats and glass/Kevlar mats. This design improves the shear and impact strength of the energy storage devices.

Interpretable Multi-Head Self-Attention Architecture for Sarcasm Detection

2021-113 – The University of Central Florida invention is an interpretable deep learning model to detect sarcasm within social media text. Since social media enables businesses to advertise their products, build brand value, and reach out to their customers, businesses need to process customer feedback in posts and tweets. Sentiment analysis identifies the emotion, either positive, negative,... Read More

Single-Shot Low-Light Polarimeter

2021-098 – The University of Central Florida invention is a type of polarimeter. Its self-referencing nature makes it ideal for accurately measuring the properties of beams in any state of polarization, regardless of their direction of incidence. The compact design and single-shot operation make the invention useful in time-resolved remote sensing applications. Moreover, the design uses all... Read More

High Power In-Band Pumped, Triple Clad Thulium Fiber and Laser Modeling Software

2021-093 – The University of Central Florida invention is a thulium fiber geometry design specifically geared for in-band pumping. Thulium-doped fiber lasers have gained much interest recently in the field of directed energy because of the potential to create eye-safe sources at 2 μm. This design will take advantage of the higher efficiencies and lower thermal load of in-band pumping. The... Read More

Low Cost, Eco-Friendly Technique for Gas-Phase Migration of Metal Oxides at Ambient Pressure

2021-104 – The University of Central Florida invention is a novel gas-induced metal migration and deposition (GIMMD) technique at ambient pressure. The invention can provide an effective and environmentally benign approach for metal or metal-oxide coating on specific substrates, as well as the synthesis of new generation, cost-effective catalytic materials for chemical, energy and... Read More

Multi-Agent Open Distribution System Simulator

2021-096 – The University of Central Florida invention is a Multi-Agent Open Distribution System Simulator (MA‐OpenDSS). The invention is built on OpenDSS and incorporates asynchronous local communication, dynamic behaviors of distributed resources, and a host of distributed optimization and control algorithms. This software has applications in electric power systems and utility industries.... Read More

Customizable 3D Microelectrode Array with Tri-Modal Functionalities

2021-109 – The University of Central Florida invention is a polymer and metal-based microfabrication technology for 3D microelectrode arrays (3D MEAs). The device incorporates “tri-modal functionality” for obtaining simultaneous data sets comprising electrical, optical and microfluidic markers from a variety of electrogenic cellular constructs. 3D MEAs are the next-generation interfaces for... Read More

Pneumatic-Hydraulic Hybrid Variable Stiffness Design for Ankle-Foot Prostheses

11643 – The University of Central Florida invention relates to a new design for ankle-foot prostheses that incorporates a hybrid closed loop pneumatic and hydraulic system to control the level of stiffness and energy return timing during walking.

Multi-Element Laser-Based Full-Duplex Free-Space Optical Transceiver

2021-078 – The University of Central Florida invention is a genetic algorithm framework to explore optimized multi-element free-space optical (FSO) transceiver tiling patterns to ensure maximal signal-to-interference and noise ratio (SINR). The framework also serves to minimize the effects of vibration of the mobile platform and atmospheric turbulence. With the ever-growing demand for... Read More

Hybrid Photonic Iterative Solver for Large-Scale Systems of Equations

11650 – The University of Central Florida invention relates to a method of solving a linear equation system for use in matrix inversion, image reconstruction, high–dimensional inverse problems, numerical eigen problems, and ab initio ray-tracing engines.

All-Solid-State Lithium (Li) Rechargeable Battery With Prolonged Life and Stable Charge/Discharge Performance

11654 – The University of Central Florida invention describes the cell structure of an all‐solid‐state lithium secondary battery. The proposed design enables uniform lithium deposition to prevent the formation of dendrites. In addition, the design allows a controlled growth of lithium towards a specific direction into a designated area in the cell. The use of lithium metal anodes causes... Read More

Zn-Based Alloys for High-Performance and Long-Cyclability Aqueous Batteries

11656 – The University of Central Florida invention is a universal strategy for designing a high-performance, safe, alloy anode for aqueous (water) batteries. Metal anode instability, including dendrite growth, metal corrosion, and hetero-ions interference, occurring at the electrolyte/electrode interface of aqueous batteries, are among the most critical issues hindering their widespread... Read More

Optically-Pumped Semiconductor Waveguide Amplifier

11538 – The University of Central Florida invention is a device that incorporates a conventional laser monolithically integrated with a totally undoped semiconductor optical amplifier (SOA) that can produce more than 20dB of optical gain in an overall length of less than 100 μm. A 2-D array of such devices can easily be flip-chip bonded onto a silicon photonic integrated circuit (PIC) for... Read More

Pulse Compression and Supercontinuum Generation Scheme Using Random Glass-Air Anderson Localization Fiber

2021-083 – The University of Central Florida invention demonstrates pulse compression and supercontinuum generation in optical fibers with transverse random and longitudinal uniform refractive index distributions.

Instantaneous Non-Diffracting Light-Sheet Generation Using Controlled Spatial Coherence

11553 – University of Central Florida researchers have developed an easily implementable method for enhanced high‐resolution, light‐sheet fluorescence imaging without using a beam scanning module or a phase modulation system. The UCF single-shot, non-diffracting light-sheet generation technique provides a much larger field-of-view and higher signal-to-background ratio than current... Read More

A Comprehensive System for Structural Health Monitoring at a Global Level Using Computer Vision

2021-072 – The University of Central Florida invention describes a comprehensive system for structural health monitoring at a global level using computer vision. The system integrates different algorithms and methods to develop a structure-oriented, computer vision-based structural response monitoring framework. It provides a guide for different structures in different application scenarios... Read More

Convenient, Self-Sterilizing Rollable Face Mask for Everyday Use

2021-057 – Researchers at the University of Central Florida have designed a face mask that conveniently rolls into a necklace-like device that also sterilizes the mask when not in use. The World Health Organization (WHO) and the U.S. Centers for Disease Control and Prevention (CDC) strongly recommend wearing a mask to prevent infections and to mitigate the spread of contagious diseases such... Read More

Ultrashort Pulse Field Measurement Device

2021-066 – The University of Central Florida invention is a system for measuring the electric field (amplitude and phase) of a femtosecond laser pulse, consisting of a spatial filter, a beam splitter, an optical delay line, a cylindrical or spherical focusing element, and a detector. The detector can consist of either (a) a transparent crystal, a set of imaging lenses, and a spectrometer (or... Read More

Multi-Stage Raman Amplifier

11533 – The University of Central Florida invention is a multi-stage diamond Raman Master Oscillator Power Amplifier (MOPA). Raman lasers, in general, do not require rare-earth doping, as the vibrational modes of the atomic structure or crystal lattice are the media for the effect. It is a nonlinear effect, and as such, the gain is proportional to the intensity of the 1st Stokes signal and... Read More

Tailored Laser Pulse Trains for Burst-Mode Illumination

11534 – The University of Central Florida invention is a novel laser that generates directed energy at a distance consisting of a narrowband tunable radio-frequency (RF) emission in the MHz and GHz ranges for military and commercial applications. This is accomplished by creating a localized transient micro-laser plasma source with a periodic pulse function. The system is additionally... Read More

Quantum Cascade Laser Tree Arrays with Broad Area Emitters Offer Ultra-High Output Power and Beam Quality

11558 – The University of Central Florida invention describes a quantum cascade laser (QCL) configuration with broad-area emitters and tapers at the output facet. The configuration potentially offers ultra-high brightness with on-axis, far-field maximum, and most power concentrated in the central lobe. Broad-area quantum cascade lasers are capable of delivering very high CW power. Output... Read More

Fast and Accurate Netlist to RTL Reverse Engineering and Netlist Assessment Toolset

11554 – Researchers at the University of Central Florida have developed two inventions for detecting code flaws and malicious logic in third-party intellectual property (IP) used to produce integrated circuits (IC): Invention Track Codes: 11554, 11555 IP Track Codes: 34393, 34421

CD25 Targeted IL-2 Therapy for Respiratory Viral Infections

11577 – Researchers at the University of Central Florida have developed a new approach for modulating the inflammatory response during acute respiratory viral infections. This approach generates a robust inflammatory response against the viral infection while minimizing damaging inflammation and immunopathology. Infections by respiratory viruses, such as influenza viruses and... Read More

Nanoceria-Based Rapid Acting Disinfectant (RAD) Spray

11585 – The University of Central Florida invention is a nanoceria-based solution for disinfectant use. Rapid Acting Disinfectant (RAD) Spray is a solution that can curb transmission of COVID-19 via contact with surfaces in a manner that is not currently available and is unique as a disinfectant spray and temporary film. Early studies have shown that these viruses can live between two to... Read More

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