Healthcare » Diagnostics

Found 16 technologies within Diagnostics RSS ATOM

Fabrication and Characterization of 3D Printed, 3D Microelectrode Arrays (MEAs) with Spin-Coated Insulation and Functional Electrospun 3D Scaffolds

33871 – New MEA Fabrication Technology Enables the Development of Rapid Assays with 3D Cell-Based Biosensors for Toxicity Testing, Disease Modeling and Optical/Electrical Stimulation of Cell Types Exploded view of the 3D MEA: 3D microtowers, metallization, laminate insulation and containment culture well with a close-up of 10 recording sites per patch. Fully functional for “disease in a... Read More

Genetic Markers and Therapeutic Targets for Diagnosis and Treatment of Rheumatoid Arthritis

11283 – Newly identified association between single nucleotide polymorphisms and intestinal bacteria in rheumatoid arthritis patients may provide new approaches for treatment Rheumatoid arthritis (RA) is a chronic inflammatory disease that has been linked to infectious agents such as the bacteria, Mycobacterium avium subspecies paratuberculosis (MAP). While the exact cause of RA is unknown,... Read More

Diagram (a) illustrates the new UCF 3D-printing technique used to produce 3D-printed porous scaffolds for cell culture. Image (b) shows the honeycomb design of scaffolds and the actual appearance of scaffolds with different processing routes after recovery from a gelatin bath. Recovered prints were immersed in cell culture media to reveal pore formation with the existence of bubbles inside the struts. Scale bars are 10mm.

3D-Printing Technique for Creating Biomaterial Structures with Tailored Hierarchical Porosity

33859 – Novel printing technique enables the production of custom porous 3D printed biomaterial scaffolds UCF researchers have developed a new 3D printing technique to produce biomaterial scaffolds with controlled porosity. This technique enables the design and production of 3D printed structures with pores throughout the scaffold, providing additional sites for seeded cells to adhere and grow. ... Read More

Prostate cancer C4-2B cells on different stiffness CA scaffolds. Mineralizationincreases with stiffness.

3D Biomaterial Scaffolds Mimic Tumor Microenvironment and Enable Drug Screening for Personalized Cancer Therapies

33849 – New 3D biomaterial scaffold enables testing of chemotherapies before administering to patients Researchers at UCF and the Mayo Clinic are developing a diagnostic tool for predicting patient outcome in response to a particular cancer treatment. The tool consists of biomaterial scaffolds that mimic the in vivo 3D structure of the tumor microenvironment and can be used as an in vitro platform... Read More

UCF’s Young Adult and Adolescent Male Health Behavior Indicators Scale enables health organizations to gain deeper insight into the health-related attitudes, perceptions and experiences of YAAM populations and the health disparities that they encounter.

Assessment Tool Identifies Male Behavior and Attitudes Toward Healthcare

33783 – Survey Tool Enables Researchers to Capture Critical Data about Promoting Health Services to Young Adult Males UCF researchers have developed a valuable survey tool that can help organizations improve their healthcare service and delivery systems aimed at young adult and adolescent males (YAAMs). With the Young Adult and Adolescent Male Health Behavior Indicators Scale, health... Read More

Decision Support System Helps Hospitals Prevent Heart Failure Readmissions

33648 – Low-cost, innovative support tool enables care managers to implement interventions that prevent readmissions and improve the health outcomes of patients with heart failure UCF researchers have invented a decision support tool for enhancing patient care and reducing hospital readmissions related to heart failure (HF). The innovative support tool identifies and analyzes patient-centric human... Read More

Figure 1. Left image: Dotted red lines show the abdominal region boundaries on the left. Right image: A thin discontinuous muscle wall (dotted blue curve) separates VAT and SAT.

First Automated System to Quantify White and Brown Adipose Tissue at the Whole-Body, Body-Region and Organ Levels

33690 – Innovative system enables clinicians to better assess health risks of obese patients by accurately identifying and quantifying body fats UCF researchers have developed the first automated system to provide accurate, quantitative data regarding a person’s white and brown body fat (adipose tissue) levels. The innovation enables clinicians to better assess possible health issues and risks... Read More

Breakthrough Optical Blood Coagulation Monitor Provides Real-time Feedback

31064 – Life-saving device continuously checks a patient’s blood clotting status during and after surgery UCF researchers have developed a breakthrough early-detection system that helps detect life-threatening blood clots during and after a medical procedure. Conventional laboratory blood coagulation tests are time-intensive, requiring blood to be drawn, processed and analyzed. The UCF real-time... Read More

Schematic representation of the fabrication and use of the ISE.

Ready-to-Use Paper Ion Sensor for On-Site Analysis

33425 – Ion-selective electrodes (ISEs) are highly important for ion detection. Paper-based ISEs are a simple, low cost, and disposable alternative to conventional solid-contact ISEs. However, widespread use of paper-based ISEs has been limited due to poor detection limits (in the micromolar range), reliability, and selectivity. UCF researchers have developed novel ultra-sensitive paper-based ISEs... Read More

Rapid, Cost-Effective Test for Mycobacteria

33286 – UCF researchers have discovered a rapid, cost-effective method to test samples for mycobacterial infection. This measurement can be obtained by assaying a biological sample from the subject, providing a more cost effective, less labor intensive testing process. Once a mycobacterium is identified, this method can be further used to monitor the infection after treatment with an antibiotic. ... Read More

The Dementia and Delirium Analysis Research Tool

33410 – An easy-to-use, accessible questionnaire that both clinicians and caregivers can use with dementia and delirium patients Currently, screenings for delirium and dementia are performed separately and administered by a trained professional. However, this process is inconvenient and time consuming for both the clinician and the patient, often leading to misdiagnoses in busy clinical settings... Read More

Perspective view of a first preferred embodiment of the novel probe and receiver device for simultaneous acquisition of spatial and spectral OCT (SI-OCT)

Simultaneous Spatial Imaging and Spectral Sensing for the Diagnosis of Cervical and Skin Cancers

30450 – A probe that simultaneously performs optical coherence tomography (OCT) and spectral analysis using back reflected light The present invention provides a tunable source of low-coherence light to simultaneously conduct spatial imaging and spectral sensing for tissue diagnosis. It offers a real time three dimensional colposcopy diagnosis and the detailed guidance to physically biopsy... Read More

Scheme showing microarrays of enzyme assisted probes

Fluorescent Detection of Nucleic Acid Sequences using Binary Probes System

32131 – This invention is a new enzyme-assisted detection system for analyzing nucleic acids with real-time fluorescent signal generation Detection of nucleic acid sequences is critical for disease diagnosis, drug development, biomedical research, and forensic testing. A nucleic acid reporter is commonly used for the detection of specific sequences. This reporter probe is labeled with a... Read More

Cerium oxide coated electrode with electronic circuit

Faster Detection of Free Radicals

30949 – A nanoceria based regenerative radical sensor for plasma testing, food quality control, or drug development UCF researchers have developed an electrochemical sensor for the measurement of free radicals, or materials that generate free radicals, in solution. Ideal for biomedical, pharmaceutical, or sensor companies, this sensor has a long lifetime with the option of multiple uses. With an... Read More

Flow chart that shows steps in an example method for forming functionalized particles, according to an example embodiment

Micro- and Nano-Scale Polymeric Particle Fabrication

33036 – By forming a polymer casing that can encapsulate nanoparticles to deliver them to specific locations in the human body based on the polymer spheres’ shape, researchers have developed a technology to advance biomedical treatment and diagnosis. This ability to produce polymeric particles with a size, shape, and composition that determines finely-tuned physiochemical properties is made more... Read More

Design of a nanoparticle-based assay for the identification of genomic markers of the intracellular pathogen Mycobacterium avium spp. paratuberculosis.

Rapid Genomic Identification of Pathogens

32151 – Using hybridizing Magnetic Relaxation Nanosensors (hMRS) Microoganims associated with disease or contamination of the environment present serious challenges that threaten public health. For example: pathogenesis relies on the survival of microorganisms within host cells, such as macrophages and dendritic cells, or tissue. This mode of infection, with or without clinical symptomology,... Read More